Tuberculosis

Tuberculosis

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. While many people infected with TB bacteria do not fall ill immediately (latent TB infection), some develop active TB disease, which can be life-threatening if not treated. TB most commonly affects the lungs (pulmonary TB), but it can also involve other organs such as the brain, kidneys, spine, and lymph nodes.

Key National Indicators
  • TB incidence reduced by 21%, from 237 per lakh population (2015) to 187 per lakh population (2024)
  • The decline is almost double the global average reduction (12%)
  • TB mortality reduced by 18%, from 28 per lakh (2015) to 23 per lakh population
  • India achieved >80% treatment coverage, one of the highest among the 30 high TB burden countries

Symptoms
  • A bad cough that lasts 3 weeks or longer
  • Pain in the chest
  • Coughing up blood or sputum (phlegm) from deep inside the lungs
  • Weakness or fatigue
  • Weight loss
  • No appetite
  • Chills
  • Persistent low grade fever
  • Sweating at night.

Transmission

TB spreads from person to person through the air.

  • When a person with active pulmonary TB coughs, speaks, sneezes, or sings, TB bacteria are released into the air
  • Others may become infected by inhaling these airborne bacteria
  • Untreated TB patients can infect 10-15 people in a year through close and prolonged contact.

Testing

Tests for TB Infection

  • TB blood test (IGRA)
  • TB skin test (Mantoux test; Cy-TB)

A positive test indicates TB infection but does not confirm disease.

Tests for Active TB Disease

  • Chest X-ray
  • Sputum examination (microscopy / molecular tests)
  • Positive disease tests → Active TB
  • Negative disease tests → Likely latent TB or no TB

Treatment

TB is largely curable when diagnosed early and treated correctly.

  • Standard treatment includes a combination of 4 anti-tuberculosis medicines
  • Treatment duration: 6 months (or 4 months in selected cases)
  • Strict adherence to treatment is essential

Prevention

TB can be prevented at both individual and population levels.

Key Prevention Measures

  • TB Preventive Treatment (TPT) for people at high risk
  • Early screening and diagnosis
  • Addressing risk factors:
    • Undernutrition
    • HIV
    • Diabetes
    • Tobacco and alcohol use
    • Poverty and overcrowding

Vaccination

  • BCG vaccine provides protection against severe TB forms in children

Why Early Action Matters
  • TB is curable and preventable
  • Delayed diagnosis increases transmission and complications
  • Early testing protects families, communities, and workplaces

References
  1. Central TB Division, Government of India. India TB Report 2024. Available at https://tbcindia.mohfw.gov.in/wp-content/uploads/2024/10/TB-Report_for-Web_08_10-2024-1.pdf
  2. World Health Organization. Global TB Report 2025. Available at https://www.who.int/teams/global-programme-on-tuberculosis-and-lung-health/tb-reports/global-tuberculosis-report-2025
  3. Ministry of Health & Family Welfare, Government of India. Available at https://www.mohfw.gov.in/?q=en/pressrelease-338
  4. Centers for Disease Control and Prevention. TB Signs & Symptoms. Available at https://www.cdc.gov/tb/signs-symptoms/index.html